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What is “Psoriasis: consensus & controversies”?
"Psoriasis: consensus & controversies" is a forum between psoriasis experts from all around the world. The main goal is to build a multi-opinion document highlighting the different therapeutic strategies in the world. This approach allows to gather the large diversity of experiences and opinions and is the best way to identify major questions; hence, it is the motor of clinical research.
This debate is initiated by an informal paper, aiming to stimulate the expression of opinions, proposed by L. Dubertret.
The text is organized in several chapters. You can have updated references on the topics discussed in this document by clicking on the underlined words. To see the comments made by other experts, please click on the name of the author on the right side of the page.
3. THE PHYSIOPATHOLOGY OF PSORIASIS
4. CLINICAL ASPECTS AND VARIATIONS
6. DEVELOPMENT AND TRIGGER FACTORS
10. ASSESSING THE SEVERITY OF PSORIASIS AND ITS EVOLUTION UNDER TREATMENT
13. MANAGING DIFFERENT KINDS OF PSORIASIS
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- 1.
PREFACE
- 2.
HISTORICAL OVERVIEW
- 3.
THE PHYSIOPATHOLOGY OF PSORIASIS
- 3.1. Psoriasis is a genetic disorder
- 3.2. Psoriasis: a non-inhibited normal healing process
- 3.3. Psoriasis is maintained by neutrophils
- 3.4. Psoriasis is the outcome of a skin cells anomaly
- 3.5. Psoriasis is the outcome of an anomaly of the interactions between dermis and epidermis
- 3.6. Psoriasis is an illness resulting from the activation of certain subpopulations of T lymphocytes
- 3.7. What can be learned from physiopathological studies for patient information purposes?
- 4.
CLINICAL ASPECTS AND VARIATIONS
- 5.
HISTOPATHOLOGY
- 6.
DEVELOPMENT AND TRIGGER FACTORS
- 7.
PSORIATIC ARTHRITIS
- 7.1. Clinical manifestations
- 7.2. Radiological symptoms
- 7.3. Evolution
- 7.4. Treatment
- 8.
DIFFERENTIAL DIAGNOSIS
- 9. STRATEGY OF TREATMENT
- 10. ASSESSING THE SEVERITY OF PSORIASIS AND ITS EVOLUTION UNDER TREATMENT
- 11.
TREATMENTS
- 11.1. Topical Treatments
- 11.2. Systemic Treatments
- 12.
THERAPEUTIC STRATEGIES
- 12.1. The classic strategy
- 12.2. Crisis situations
- 12.3. Maintenance therapy
- 12.4. Combination therapies
- 12.5. Alternate treatments
- 12.6. When all treatments fail
- 12.7. Psychological management
- 13. MANAGING DIFFERENT KINDS OF PSORIASIS
- 14.
HOPES FOR THERAPY
- 15.
CONCLUSION




